Statins may reduce risk of depression

Statins and Thyroidectomy May Reduce the 
Risk of Orbitopathy Developing in Patients with 
Graves’ Disease

Background Graves’ orbitopathy (GO) is a component of Graves’ disease (GD) that is difficult to treat and may be very debilitating for the patient. Orbitopathy (ophthalmopathy [harder to pronounce]) is a significant problem for about 5% to 10% of patients with Graves’ disease. The factors that cause a predisposition to it are not clear. The current study examines a database of patients with Gra...

Statins May Lower Lung Cancer Risk

Aromatase inhibitors may reduce endometrial cancer risk.

Use of aromatase inhibitors, which are known to reduce endogenous oestrogen levels, as adjuvant therapy had a lower risk of endometrial cancer, compared with that of patients who were treated with tamoxifen, results of a new study show. In this study, Rowan Chleblowski and colleagues (Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Los Angeles, CA, USA) examined the rec...

Finasteride and dutasteride may reduce melanoma risk.

Malignant melanoma is an androgen-dependent tumor. Androgen blockade enhances response to the melanoma vaccine. In their study, Zhang et al reported that a history of teenage acne in women may be a novel risk factor for melanoma independent of other risk factors. Acne in women is related to androgens and can be treated with finasteride. Both finasteride and dutasteride prevent the conversion of...

Statins may reduce femoral osteolysis in patients with total Hip arthroplasty.

In experimental studies, statin use has been associated with reduction of osteoclastic activity and promotion of bone formation around implants. Moreover, a large clinical study recently reported a substantially reduced risk of revision for aseptic loosening among statin users with THA. Our objective was to evaluate the influence of statin use on the development of femoral osteolysis within 5 y...